1. What is Allele Frequency?

Allele frequency is the relative frequency of an allele (variant of a gene) at a particular locus in a population. It shows how common an allele is in a population.

2. How Does the Calculator Work?

The calculator uses the allele frequency equation:

Where:

• \( number\_allele \) — Count of the specific allele in the population
• \( total\_alleles \) — Total number of alleles at that locus in the population

Explanation: The equation calculates the proportion of a specific allele among all alleles at that genetic locus.

3. Importance of Allele Frequency

Details: Allele frequencies are fundamental in population genetics, used to study genetic variation, evolution, and disease risk in populations.

4. Using the Calculator

Tips: Enter the count of the specific allele and the total number of alleles. Both values must be positive numbers, with number_allele ≤ total_alleles.

5. Frequently Asked Questions (FAQ)

Q1: What's the range of possible allele frequencies?
A: Allele frequencies range from 0 (allele absent) to 1 (fixed allele present in all individuals).

Q2: How is this different from genotype frequency?
A: Allele frequency counts individual alleles, while genotype frequency counts combinations of alleles in individuals.

Q3: What is the Hardy-Weinberg equilibrium?
A: A principle stating allele frequencies remain constant from generation to generation in the absence of evolutionary influences.

Q4: When would allele frequency change?
A: Due to natural selection, genetic drift, mutation, gene flow, or non-random mating.

Q5: How is this used in medical genetics?
A: To determine population risk for genetic diseases and track disease-associated alleles in populations.