1. What is Heparin Infusion Calculation?

The heparin infusion calculator determines the appropriate infusion rate (in mL/h) based on the ordered dose, stock concentration, and volume of the solution. This is crucial for safe and effective anticoagulation therapy.

2. How Does the Calculator Work?

The calculator uses the heparin infusion formula:

Where:

• Ordered Dose — Desired heparin administration rate in units per hour
• Stock Strength — Concentration of heparin in the available solution (units per mL)
• Volume — Total volume of the heparin solution bag

Explanation: The formula calculates how many mL of the heparin solution need to be infused each hour to deliver the prescribed dose.

3. Importance of Accurate Heparin Dosing

Details: Heparin has a narrow therapeutic window. Accurate dosing is critical to balance between therapeutic anticoagulation and bleeding risks. Regular monitoring of aPTT or anti-Xa levels is typically required.

4. Using the Calculator

Tips: Enter the ordered dose in units/h, stock strength in units/mL, and volume in mL. All values must be positive numbers. Double-check your inputs against the medication order and available heparin solution.

5. Frequently Asked Questions (FAQ)

Q1: Why is heparin dosed in units rather than mg?
A: Heparin's potency varies between preparations, so it's standardized in units rather than weight measurements.

Q2: What are common heparin concentrations?
A: Common concentrations include 25,000 units/500 mL (50 units/mL) or 25,000 units/250 mL (100 units/mL).

Q3: How often should heparin infusions be adjusted?
A: Typically every 6 hours after aPTT results, following institutional protocols.

Q4: What if my institution uses weight-based dosing?
A: First calculate units/h based on patient weight (e.g., 18 units/kg/h), then use this calculator.

Q5: Are there special considerations for pediatric patients?
A: Yes, pediatric dosing often requires more frequent monitoring and may use different concentration standards.