1. What is Globulin?

Globulin is a group of proteins in your blood that includes antibodies, enzymes, and other important proteins. It's calculated by subtracting albumin from total protein in a blood test.

2. How is Globulin Calculated?

The calculation is simple:

Where:

• Total Protein — Measured in g/dL (typically 6.0-8.3 g/dL)
• Albumin — Measured in g/dL (typically 3.5-5.0 g/dL)

3. Clinical Significance

Details: Globulin levels help evaluate liver function, immune system status, and can indicate various conditions like chronic inflammation, autoimmune diseases, or certain cancers when abnormal.

4. Using the Calculator

Tips: Enter both total protein and albumin values in g/dL. The total protein must be equal to or greater than the albumin value.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal globulin level?
A: Typically 2.0-3.5 g/dL, though ranges may vary slightly by laboratory.

Q2: What does high globulin mean?
A: May indicate infection, autoimmune disease, chronic inflammation, or certain cancers like multiple myeloma.

Q3: What does low globulin mean?
A: May suggest liver or kidney disease, malnutrition, or immune deficiency.

Q4: How does this relate to A/G ratio?
A: The Albumin/Globulin ratio (A/G ratio) is another important measure, normally about 1.0-2.0.

Q5: When should I get my globulin checked?
A: As part of routine comprehensive metabolic panel or when evaluating liver disease, immune disorders, or unexplained symptoms.