1. What is Genotype Frequency?

Genotype frequency is the proportion of a particular genotype in a population. It is calculated by dividing the number of individuals with a specific genotype by the total number of individuals in the population.

2. How Does the Calculator Work?

The calculator uses the genotype frequency equation:

Where:

• Number of individuals with genotype — Count of individuals having the specific genotype
• Total number of individuals — Total population size being studied

Explanation: The equation gives the relative frequency of a genotype in a population, ranging from 0 (absent) to 1 (all individuals have this genotype).

3. Importance of Genotype Frequency

Details: Genotype frequencies are fundamental in population genetics, helping to understand genetic variation, Hardy-Weinberg equilibrium, and evolutionary processes.

4. Using the Calculator

Tips: Enter the count of individuals with the genotype and the total population size. Both values must be positive integers, with the observed count not exceeding the total.

5. Frequently Asked Questions (FAQ)

Q1: What's the difference between genotype and allele frequency?
A: Genotype frequency counts combinations of alleles in individuals, while allele frequency counts how often an allele appears in the gene pool.

Q2: What are typical genotype frequency values?
A: Values range from 0 to 1. In Hardy-Weinberg equilibrium, frequencies follow p², 2pq, q² for AA, Aa, aa genotypes.

Q3: When is genotype frequency used?
A: Used in genetic studies, disease association research, conservation genetics, and evolutionary biology.

Q4: Are there limitations to genotype frequency?
A: Accuracy depends on representative sampling. Small samples may not reflect true population frequencies.

Q5: How does this relate to allele frequency?
A: Allele frequencies can be calculated from genotype frequencies by counting alleles in the population.